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IOP-lowering efficacy from latanoprost, without preservatives

In randomized, controlled clinical trials of patients with mean baseline IOP as low as 19 and as high as 24 mmHg,* IYUZEH™ (latanoprost ophthalmic solution) 0.005% showed proven efficacy through clinically meaningful IOP reductions.1-3

IOP-Lowering Effects of IYUZEH™ Across Clinical Trials1-4

A chart comparing intraocular pressure lowering effects of Iyuzeh to Xalatan in Phase 3 clinical trials.
A chart comparing intraocular pressure lowering effects of Iyuzeh to Xalatan in Phase 3 clinical trials.

*In the US clinical trial, the mean IOP baseline was 18.8 mmHg for IYUZEH (n=165) and 19.2 mmHg for XALATAN® (n=169) compared with 24.1 mmHg for IYUZEH (n=189) and 24 mmHg for XALATAN (n=164) in the European clinical trial, accounting for the smaller yet still clinically meaningful IOP-lowering effect.1-4

XALATAN is a registered trademark of Pfizer PFE Holdings 4 LLC, a Viatris Company.

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IYUZEH has been demonstrated effective in 7 studies with a total of 3746 patients across the globe.1,5

Hear what your colleagues are saying about IYUZEH

In the study, there was a very important differentiating factor that most new agents don’t have–the bar. And the bar in this study was branded XALATAN. Most of the Phase III trials for approval of medicines in the US for glaucoma and ocular hypertension, the comparator is beta blockers. And so, for IYUZEH, in its pivotal studies, to go against XALATAN, that’s a pretty high bar.

Jason M. Bacharach, MD

Dr. Bacharach is a paid consultant of Thea Pharma Inc.

Visit our Video Library to Hear Why Eye Care Professionals are Choosing IYUZEH

Things your patients may not say, but could be thinking

Eileen, Seeking Efficacy Without Extra Ingredients

Eileen has been on a latanoprost generic for a few years and has done her homework on the different ingredients in ophthalmic solutions that lower IOP. While she’s really interested in a treatment without benzalkonium chloride (BAK), she doesn’t want to risk any increase in IOP.

Eileen heard about IYUZEH – the first and only preservative-free latanoprost. With the help of her eye care professional, she switched and is very satisfied with her treatment.

Patient portrayal. Not an actual patient.

Meet Eileen. Learn why switching to a preservative-free latanoprost may be an option for your patients.
Meet Eileen. Learn why switching to a preservative-free latanoprost may be an option for your patients.

Eileen has been on a latanoprost generic for a few years and has done her homework on the different ingredients in ophthalmic solutions that lower IOP. While she’s really interested in a treatment without benzalkonium chloride (BAK), she doesn’t want to risk any increase in IOP.

Eileen heard about IYUZEH – the first and only preservative-free latanoprost. With the help of her eye care professional, she switched and is very satisfied with her treatment.

Patient portrayal. Not an actual patient.